• After Counterfeit Avastin Infiltrates Supply Chain, FDA Goes After Doctors

    The US Food and Drug Administration (FDA) is going after doctors in an attempt to protect the pharmaceutical supply chain from more instances of counterfeit medicines, reports Medscape News . There have been two instances of fake Avastin being found in the US in 2012-one in early April and another in mid-February . Both cases involved doctors deviating from approved suppliers to purchase Avastin from unauthorized wholesalers. While FDA Commissioner Margaret Hamburg ...
  • NICE Denies Avastin Indication for Breast Cancer

    The UK's National  Institute for Health and Clinical Excellence (NICE) announced in a draft guidance it will not approve Roche's breast cancer drug Avastin (bevacizumab) due to "too many uncertainties" about the drug's cost effectiveness, writes In Pharm . "The draft guidance, which is out for consultation, has not recommended Avastin as first line treatment for metastatic breast cancer in combination with chemotherapy drug capecitabine," wrote In Pharm . NICE's ...
  • Report: Second Instance of Fake Avastin Highlights MHRA Troubles

    Another incident involving lots of fake bevacizumab (Avastin/Altuzan)-the second in as many months-is drawing attention to resource shortages at the UK's Medicines and Healthcare product Regulatory Agency (MHRA), reports Reuters . The British healthcare product regulator currently oversees 1,800 wholesalers in the country-second in amount only to Germany, which oversees more than 3,000 wholesalers. "We are concerned that the MHRA doesn't have sufficient resources to in...