Science & Technology: Mitochondria and Mitochondrial Diseases—Badly Kept Secrets

| 01 October 2010

It would appear there is neither any link nor any obvious similarities among Parkinson's disease, exercise intolerance, diabetes and organ failure in sepsis except that each is a health problem. Anything else common to this disparate group would have to be quite fundamental. Such is the case: we now know that the common link is the mitochondrion, which has been deemed the mighty dynamo of the cell.1 Each of the conditions listed results from a pathology that inhibits mitochondrial activity and results in failure to provide the necessary energy for normal metabolic processes.


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