Recon: FDA approves lower dose of Lilly-Incyte arthritis drug

• ‘Right-to-try’ law intended to weaken the FDA, measure’s sponsor says in blunt remarks (STAT) (Endpoints) (Fierce) (Washington Examiner) (MedCity News)
• Amgen, MD Anderson Launch Two Cancer Collaborations (GEN News) (Fierce)
• Neoantigen pioneer Neon Therapeutics casts off in search of $115M IPO to fuel the race to a personalized cancer treatment (Endpoints) (Fierce)
• Celgene shakeup continues: Johnson & Johnson veteran Elkins joins as CFO months before Kellogg retires (Fierce) (Endpoints)
• FDA approves lower dose of Lilly-Incyte arthritis drug (Reuters) (STAT-$) (Endpoints)
• J&J racks up a fresh set of positive pivotal data for depression drug esketamine — but questions linger on safety (Endpoints) (The Pharma Letter-$)
• Oncologists sue HHS over Medicare Part B sequester cuts (Modern Healthcare) (Medscape)
• Thanks to lower-than-expected price, ICER backs Amgen's Aimovig—but only after other drugs fail (Fierce) (PMLiVE)
• Xynomic Pharma completes Series B fundraising, sets sights on Abex development (The Pharma Letter) (Fierce)

• Roche scraps €120M SMA drug after hitting ‘many difficulties’  (Fierce) (PharmaTimes) (Endpoints) (GEN News)
• Tesaro's ovarian cancer drug Zejula added to Cancer Drugs Fund (PharmaTimes) (The Pharma Letter-$) (PMLiVE)
• UN health agency backs away from call to tax sugary drinks (AP News) (Reuters)
• Fragile Antibiotic Supply Chain Causes Shortages And Is A National Security Threat (Forbes)
• World’s first cancer app to integrate with an EMR as Australia’s CancerAid links into Cedars-Sinai’s Epic system (Healthcare IT News)

• Biotech CEO Pay: Inflation Held At Bay (Forbes)
• The FDA is sounding the alarm on the next group of drugs that could be abused (Business Insider)
• Bayer and MD Anderson collaborate on novel targeted cancer treatments (pharmaphorum)
• Leading oncology group wary of Trump drug price proposals (Reuters)
• Drug costs prompt fears of ‘financial toxicity’ in cancer care (Financial Times)
• Opinion: Putting Patients First in Drug-Pricing Decisions (Morning Consult)
• Drug makers push back on cost-effectiveness research for Medicare drugs (STAT-$)
• FDA wants brand and generic drug makers to get along (Axios)
• Sanofi tweaks pricing policies, discloses 8.4% net price decline in 2017 (Fierce)
• Amgen is the latest drugmaker to have a Herceptin biosim sidelined by a CRL (Fierce)
• Dova reveals $9K to $13.5K Doptelet price, stock sags (BioPharma Dive) (Press)

• The difficult search for the right recipe in cancer immunotherapy (C&EN)
• Next-Generation Therapies in Focus at Year's Top Cancer Meeting (Bloomberg)
• Microbiome, Herbal Medicine, and Probiotics Combine to Extend Lifespan (GEN News)
• Ahead of ASCO, BMS' Opdivo leads Merck's Keytruda in U.S. sales—but not for long, analyst predicts (Fierce) (Press)
• Small molecule silences cancer-driving RNA, opens up previously undruggable targets (Fierce)
• Samsung Bioepis Announces Results of Additional One-Year Follow-up Study on SB3 Trastuzumab Biosimilar Candidate at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting (Press)
• Aratana Therapeutics Files for FDA Approval of NOCITA (bupivacaine liposome injectable suspension) Label Expansion (Press)
• Halozyme Identifies Plasma Biomarkers As Potential Predictors Of Survival In Pancreatic Cancer (Press)
• SELLAS Life Sciences Provides Clinical Update on Phase 2b NeuVax (nelipepimut-S) Study in Combination with Trastuzumab in HER2 1+/2+ Breast Cancer Patients (Press)
• Exelixis Announces Further Expansion to Clinical Research Protocol for Phase 1b COSMIC-021 Trial of Cabozantinib in Combination with Anti-PD-L1 Immunotherapy in Patients with Locally Advanced or Metastatic Solid Tumors (Press)
• Immunomedics Announces Pivotal Study of Sacituzumab Govitecan in Patients With Locally Advanced or Metastatic Urothelial Cancer (Press)
• Data Highlighting Advaxis’ ADXS-PSA Presented at ASCO Annual Meeting (Press)
• Tonix Pharmaceuticals Presented New Data Related to Suicidal Ideation and Behaviors in Military-Related PTSD from the Phase 2 AtEase Study at the American Society of Clinical Psychopharmacology (Press)
• Lilly to Showcase New Data at Digestive Disease Week 2018 for Mirikizumab in Moderate-to-Severe Ulcerative Colitis (Press)

• Blood test offers hope of finding cancers before symptoms develop (CNN)
• As FDA signals wider AI approval, hospitals have a role to play (Healthcare IT News)
• Virgo’s technology enables video recording of colonoscopies (MedCity News)
• Telemedicine services appear to drive genetic testing (MobiHealthNews)
• Artificial Sensory Nerves May One Day Provide Prosthetic Limbs with Sense of Touch (GEN News)
• Korea’s IntroMedic wins FDA nod for MiroCam capsule endoscope, inks U.S. distro deal (MassDevice)
• Startup debuts with plan to map gene signaling pathways for new targets (Fierce)
• GE Healthcare Introduces Virtual Reality Training for Healthcare Technology Management Professionals (Press)
• Philips provides AEDs for New Cardiac Arrest Response System (Press)
• Branchpoint Technologies announces FDA 510(k) for its AURA Intracranial Pressure Monitoring System (Press)

• FDA’s Ninth Annual Report to Congress on 505(q) Citizen Petitions: New Numbers and a New Tone (FDA Law Blog)
• Mergers between health insurers and pharmacy benefit managers could be bad for your health (STAT)
• Alphabet's Verily has hired top execs to bring its science research into hospitals and homes (CNBC)
• Jamie Dimon says after health venture with Amazon and Berkshire was announced insurers were 'pissed off' (CNBC)
• CVS donated to pro-Trump "dark money" group (Axios)
• IBM Watson Health confirms layoffs (Axios)
• Trump Administration Targets State Rules That Women Must Be Told of Abortion Services (WSJ)
• Sergeant Sues Defense Dept. Over ‘Outdated’ H.I.V. Policies (NYT)
• Why the Trump administration made it easier for Virginia Republicans to expand Medicaid (The Washington Post)
• Four more die in E.Coli outbreak linked to romaine lettuce (Reuters)
• UnitedHealth expects 150M members to be in value-based programs by 2025 (Fierce)
• Planned Parenthood cancels abortion appointments in Arkansas after Supreme Court declines to hear case (The Hill)
• CMS meets MIPS reporting goals, but thousands of doctors still face penalties (Modern Healthcare)
• CMS, HHS and FDA to tech innovators: Here's how to win federal agencies as customers (Healthcare IT News)

• FDA Advisory Committee Calendar

• EMA facing higher-than-expected staff losses after Brexit (PharmaTimes)
• Samsung Phones Will Now Let You Video Chat Doctors in the UK (Fortune)
• Pharma improves reputation among German patient groups (pharmaphorum)
• PMCPA takes AZ to task over asthma drug press release (PMLiVE)
• Tela Bio, Aroa Biosurgery win CE Mark for OviTex bioscaffolds (MassDevice)
• UK’s evolution to integrated care systems will require interoperability (AllScripts)
• Bayer Science & Education Foundation launches new round of funding: EUR 350,000 for innovative project ideas (Press)

• The PD-1/PD-L1 Race in China (PharmExec)
• India's Fortis board says to consider offers from four bidders (Reuters)
• Taiwan hospitals to promote health in Asia: Health Ministry (Focus Taiwan News Channel)
• Despite gains, almost half of Southeast Asians lack basic healthcare (Southeast Asia Globe)
• Activist investor ValueAct takes $600m stake in Japan’s Olympus (Financial Times)
• Korea United Pharm wages war on Chinese fake capsules (Korea Biomedical Review)

• Delhi's proposal to cap drug costs worries Indian hospitals industry (Reuters)
• Achieving universal health coverage in India (Livemint)
• Pharma sector provides a good long-term opportunity: Sailesh Raj Bhan of Reliance Pharma Fund (Economic Times)
• Cost effective packaging innovations taking centre stage in Indian pharma industry (Pharmabiz)
• Jawed Zia joins as Vice President in Abbott, India (BioSpectrum)
• ED attaches Rs 4,701 cr assets of Gujarat pharma firm (The Telegraph)

• HBF and HCF scrap planned $4 billion health insurance merger (ABC News)

• Health Canada wants to phase out pesticides to save the bees (Health Canada)
• Health minister favours warnings on individual cigarettes as Ottawa outlines tobacco plan (The Canadian Press)

• WATCH: Surgeons create personalized brain maps to guide safer surgeries (STAT)
• Doctors are being more careful on opioid prescriptions (Axios)
• A More Egalitarian Hospital Culture Is Better for Everyone (NYT)
• A 'wake-up call' about what's killing America's young people (CNN)
• Drug Use Rankings Show Big Surprises And Even Bigger Problems (Forbes)
• When Scientists Develop Products From Personal Medical Data, Who Gets To Profit? (NPR)
• Skyping the doctor? Poll shows it’s not just for the young (AP News)
• Digital Health: "It's Not About the App" (PharmExec)
• The key to weight loss may be right in the palm of your hand (CNBC)
• Humans' Big Brains May Be Partly Due to Three Newly Found Genes (GEN News)