Recon: FDA approves Cytokinetics’ heart drug in first for drugmaker; Shionogi forges $2.5 billion buyout of Tanabe Pharma’s ALS therapy Radicava

• 3 key issues to watch at FDA as Makary struggles to stabilize the agency (STAT)
• Trump, nine pharmaceutical companies strike deal to cut prices (Reuters)
• Recalls: They Aren’t Over ‘Til FDA Says So, But Who Knows When That Will Be (FDA Law Blog)

• Ipsen adds to deal spree with ADC from Shanghai biotech Simcere Zaiming (Endpoints)
• Nine more MFN deals; Western drugmakers turn to China; Chai Discovery's raise; and more (Endpoints)
• Sputnik developer becomes head of Russia's top vaccine centre (Reuters)
• Roche CEO points to higher future drug prices in Switzerland after US deal (Reuters)
• EU proposal would simplify Medical Device Regulation (MedTech Dive)
• Finally A Happy New Year In Switzerland? (MedTech Insight)

• A seasoned biotech VC looks to 2026 and sees a wave of IPOs coming (STAT)
• ALS med Radicava to change hands as Shionogi inks $2.5B buyout (Fierce Pharma)
• Cytokinetics heart drug wins FDA approval, the biotech’s first (STAT)
• What Ozempic might tell us about the future of Alzheimer’s (STAT)
• Researchers have a moral obligation to push back when their studies are twisted to promote false health claims (STAT)
• Aktis Oncology files for IPO to fund Lilly-partnered radiopharma pipeline (Endpoints)
• AstraZeneca bets up to $2B on Jacobio’s pan-KRAS inhibitor for cancer (Endpoints)
• Boehringer taps Rectify to create pills for chronic kidney disease (Endpoints)
• AstraZeneca's ceralasertib-Imfinzi drug combo misses survival target in lung cancer trial (Reuters)
• Samsung Biologics to buy US drug production facility from GSK for $280 million (Reuters)

• Medtronic’s diabetes spinoff MiniMed files for IPO (MedTech Dive)
• Abbott receives FDA approval for Volt PFA system (MedTech Dive)
• GlucoModicum’s Needle-Free Sofio Could Offer Alternative CGM Approach (MedTech Insight)
• HHS Targets Chest Binder Vendors in New Regulatory Crackdown (MedTech Insight)
• Philips To Acquire SpectraWAVE To Expand Intravascular Imaging Portfolio (MedTech Insight)

• Study revives debate about unpopular diet for cancer patients (STAT)
• American food safety could be headed for a breakdown (STAT)

• UnitedHealthcare delays controversial RPM policy change (STAT)
• Mass General Brigham bolstered its bottom line. Other Mass. hospital groups reported multimillion losses (STAT)
• Hedge funds short healthcare providers as subsidies debate intensifies (Reuters)
• HHS seeks input on speeding AI adoption in clinical care (MedTech Dive)
• NIH study was a beacon for the topical steroid withdrawal community. Then, amid federal upheaval, the research stalled (STAT)
• Francis Collins: ‘I think of science as glimpsing God’s mind’ (STAT)