Recon: Amgen to acquire Horizon in $27.8B deal; Roche pharma CEO to step down

• Amgen dives deeper into rare disease drugs with $27.8 bln Horizon deal (Reuters) (STAT) (WSJ)
• Cancer drugmaker Clovis files for bankruptcy, hit by falling sales (Reuters)
• Patient selection for AstraZeneca, Daiichi breast cancer drug needs improvement, experts say (Reuters)
• FDA staff reviewers flag safety concerns over Cytokinetics' heart drug (Reuters)
• Pfizer sees $10 bln-$15 bln in annual mRNA vaccine revenue by 2030 (Reuters)
• Can Drugs Treat Addiction? Prisons Offer an Answer (WSJ)
• U.S. opioid crackdown hampers some patients' access to psychiatric drugs (Reuters)

• Queues form at fever clinics as China wrestles with COVID surge (Reuters)
• Too soon to call end to COVID-19 emergency, GAVI chief says (Reuters)
• Roche pharmaceuticals CEO Bill Anderson to step down after four-year tenure (STAT)
• Ebola trial candidate vaccines arrive in Uganda in record 79 days after outbreak declared (WHO)
• South Africa's Aspen gets $30 mln grant to make vaccines (Reuters)
• Some bloodstream infection bacteria grew resistant to last-resort drugs in 2020 – WHO (Reuters)
• Cambodia halts exports of non-human primates, threatening drug discovery efforts (STAT)

• Novartis develops CAR-T therapy that can be made in a fraction of the standard time (STAT)
• Argenx antibody drug benefits patients with platelet-destroying autoimmune disorder (STAT)
• Emerging class of genetically targeted drugs induce remissions in leukemia patients (STAT)
• Affimed’s natural killer cell therapy has murky path forward despite encouraging results (STAT)
• Why a tone-deaf Regeneron executive deserved to be booed over Alzheimer’s drug remarks (STAT)
• Black Diamond spins out antibody work into new biotech with $30M from Versant, NEA (Endpoints)
• Vertex, Moderna prepare to take their inhaled mRNA cystic fibrosis drug into the clinic (Endpoints)
• GSK chief Emma Walmsley picks out a trim new global HQ in downsizing move (Endpoints)
• ‘We’ve got a new target’: Bispecific antibody for multiple myeloma succeeds in mid-stage trial (STAT)
• ImmunityBio looks to pull in $157M from founder Patrick Soon-Shiong and another investor (Endpoints)

• Smiths Medical warns infusion set issues could cause false alarms, underdelivery (Fierce)
• Boston Scientific angles for majority stake with $523M for Chinese devicemaker Acotec (Fierce) (MedtechDive)
• Federal agencies release updated privacy guide for health app developers (Mobihealthnews)

• Wyden Makes Final Request to Amgen for Voluntary Compliance in Pharma Tax Investigation (Wyden)
• Theranos Cases Show How DoJ Looks Beyond The FDCA In Prosecuting Drug, Device Companies (MedtechInsight)
• J&J Unit Hit With $12M Verdict In Spinal Implant IP Suit (Law360)
• Philips Wants Latest CPAP Foam MDL Complaint Tossed (Law360)