Recon: Eli Lilly’s Omvoh bests J&J’s Stelara in late-stage study for Crohn’s; Innovation in the EU medtech market

• J&J trims pipeline, including two mid-stage neuroscience studies (Endpoints)
• Lilly’s Omvoh Beats J&J’s Stelara in Head-to-Head Phase III Crohn’s Disease Trial (BioSpace)
• J&J’s recent medtech buys help to prop up devices unit (MedTech Dive)
• Maryland biotech gets green light for stem cell-derived therapy for diabetes, aiming to compete with Vertex (Endpoints)
• GlaxoSmithKline sues Moderna for US patent infringement over COVID vaccines (Reuters)
• UnitedHealth forecasts 2025 profit below Street estimates, shares fall (Reuters)
• PBM Reform Legislation: PhRMA ‘Laser Focused’ On Passage This Year (Pink Sheet)
• Baxter bolsters IV supplies with imports to address US shortages in wake of Hurricane Helene (Fierce Pharma)

• Forbion raises €2.1B for two new biotech funds after series of company exits (Endpoints)
• Britain to study use of Lilly's weight loss drug to get people back to work (Reuters)
• Bayer submits EU marketing application for menopause relief drug (Reuters)
• Medtechs Dig Deep For UK System Positives But Take Issue With MHRA Fees Hike (MedTech Insight)
• NoBoCap: Navigating The EU Regulatory Landscape For MedTech Innovation (MedTech Insight)
• French Bill Calls For €1bn In Drug Price Cuts, Simplifies Payback (Pink Sheet)
• EU Decision Time For Hemophilia Drug Concizumab & 10 Other Products (Pink Sheet)

• Broad Institute announces layoffs, largely in IT, software engineering (STAT)
• Pfizer partners with molecular glue startup Triana in $49M upfront deal (Endpoints)
• First patient who received engineered B cell therapy sees early promise for MPS I (Endpoints)
• Cycle makes another offer for Vanda; Ocean Biomedical, Molecure ink new deal (Endpoints)
• MeiraGTx's stock rises on small Parkinson's gene therapy dataset (Endpoints)
• Tolerance Bio emerges from stealth with $17.2M to advance therapies developed from the thymus (Endpoints)
• Exclusive: Biotech tools company raises $75M for protein manufacturing tech (Endpoints)

• US FDA clears CMR Surgical's robotic device to assist gall bladder removal (Reuters)
• Hologic to buy Gynesonics for $350M to acquire fibroid system (MedTech Dive)
• Medtronic to evaluate Affera in ventricular tachycardia (MedTech Dive)
• J&J, Abbott and Intuitive kick off latest medtech earnings season (MedTech Dive)

• 11 experts on why gains in cardiovascular disease are stalling and what we can do about it (STAT)
• Otsuka calculates dementia caregivers would earn 6 figures if paid for work (Fierce Pharma)
• 5 Accelerated Approvals Gone Wrong (BioSpace)