Recon: Lilly’s bimagrumab plus Novo’s Wegovy prove potent for weight management; MHRA adds second AI airlock

• FDA chief’s goals of ‘radical transparency’ threatened by agency cuts (STAT)
• Eli Lilly drug bimagrumab saves muscle mass when added to Novo's Wegovy (Seeking Alpha)
• The decades-long journey to Gilead’s twice-a-year HIV prevention drug lenacapavir (STAT)
• Inside the FDA’s ‘listening’ tour: Officials agree US lags behind China on drug development (Endpoints)
• Last Friday was a Good Day for Those Who Want to Litigate Against the Federal Government (FDA Law Blog)

• CHMP recommends five new drugs, reconsiders Eli Lilly’s Kisunla (Endpoints)
• UK's NICE says Lilly, Eisai's Alzheimer's drugs aren't worth national coverage (Endpoints)
• Trump aid cuts deal a blow to HIV prevention in Africa (Reuters)
• China's Sciwind's GLP-1 shows similar weight loss to Novo's Wegovy, study finds (Reuters)
• Ireland Sees Thousands of Jobs at Risk From US Pharma Tariffs (Bloomberg)

• Novo Nordisk’s amylin obesity drug keeps performing like Zepbound (STAT)
• Off-the-shelf stem cell therapy for type 1 diabetes continues to show positive results (STAT) (Endpoints)
• GLP-1 reduced migraine frequency by nearly half, in a pilot study (STAT)
• Compass claims Phase 3 win in depression for psilocybin drug, moves closer to FDA filing (Endpoints)
• Illumina to buy SomaLogic for $350M upfront, pushing further into proteomics (Endpoints)
• Compass shares tumble after depression drug fails to impress (Reuters)
• Roche’s bispecific-ADC combo keeps lymphoma at bay (Fierce Pharma)

• Billionaire Hoffman Backs Brain Startup Using AI, Ultrasound (Bloomberg)
• Labcorp was the blockbuster Supreme Court case that wasn’t (Reuters)
• MHRA Opens Second AI Airlock Program For Applications (MedTech Insight)
• Stealth Mode AI Imaging Startup Faction Imaging Raises $10M (MedTech Insight)
• Remepy To Embed AI In Next-Gen Digital Therapeutics For Personalized Neuroimmune Modulation (MedTech Insight)
• Virtual Incision appoints former Intuitive exec as CEO (MedTech Dive)
• Rise in VC activity tees up ‘strong year’ for medtech funding: PitchBook (MedTech Dive)

• Grocers pressed to detail link between tariffs and food prices (Food Dive)
• FDA Seeks Input on New Method for Ranking Chemicals in Food for Post-Market Assessments (Food Safety)

• Doctors lose Medicare pay bump in Senate version of tax bill (STAT)
• Senate Republicans debate Medicaid options as hospitals move to shape legislation (STAT)
• Disagreements over Duchenne therapy, management style may have led to ouster of key FDA official (STAT)
• Pharma companies are weighing how a drug’s IP location could impact tariffs (Endpoints)